Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | BLVRB | P30043 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374507 | 0.92 | PTGS2 (0.49) | KMT2AMEN1HTTPDE4ABLVRB | |
| SCHEMBL11547404 | 0.87 | KMT2A (0.39) | KMT2AMEN1HTTPDE4ABLVRB | |
| SCHEMBL15090856 | 0.85 | MEN1 (0.48) | KMT2AMEN1HTTPDE4ABLVRB | |
| SCHEMBL8995644 | 0.78 | MAOB (0.54) | KMT2AMEN1HTTGAAPTGS2 | |
| SCHEMBL7551541 | 0.76 | KDM4E (0.46) | KMT2AMEN1HTTKDRMAPT | |
| SCHEMBL11202193 | 0.76 | ALDH1A1 (0.53) | KMT2AMEN1HTTPDE4AKDR | |
| SCHEMBL15090907 | 0.76 | PPARG (0.41) | KMT2AMEN1HTTPDE4ABLVRB | |
| SCHEMBL20258001 | 0.74 | MEN1 (0.50) | KMT2AMEN1HTTPDE4ABLVRB | |
| SCHEMBL2904410 | 0.74 | POLB (0.38) | HTTMAPTGAAL3MBTL1PTGS2 | |
| SCHEMBL379937 | 0.73 | KLKB1 (0.53) | KMT2AMEN1MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334208-A2 | METHOD FOR MARKING CHEMICAL SUBSTANCES | Friz Biochem GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002016635-A2 | METHOD FOR MARKING CHEMICAL SUBSTANCES | FRIZ BIOCHEM GMBH (DE) | 2002-02-28 | — | — | WO | disclosed |