Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090780 | 0.87 | KMT2A (0.53) | KMT2AMEN1GAAL3MBTL1NPSR1 | |
| SCHEMBL28210948 | 0.84 | PIM1 (0.44) | KMT2AMEN1GAAL3MBTL1NPSR1 | |
| SCHEMBL11374507 | 0.80 | PTGS2 (0.49) | KMT2AMEN1GAAL3MBTL1NPSR1 | |
| SCHEMBL9107343 | 0.77 | PTGS2 (0.57) | KMT2AMEN1GAAL3MBTL1NPSR1 | |
| SCHEMBL8995644 | 0.76 | MAOB (0.54) | KMT2AMEN1GAAHTTPTGS2 | |
| SCHEMBL7551541 | 0.75 | KDM4E (0.46) | KMT2AMEN1GAANPSR1MAPT | |
| SCHEMBL11202193 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL9499701 | 0.73 | MEN1 (0.58) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL2904410 | 0.73 | POLB (0.38) | GAAL3MBTL1MAPTHTTPTGS2 | |
| SCHEMBL15090856 | 0.72 | MEN1 (0.48) | KMT2AMEN1GAAL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001982-A1 | Process for preparing aromatic aminohydroxy compounds | BAYER AG (DE) | 1979-05-30 | — | — | EP | disclosed |