Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863292 | 0.83 | ALDH1A1 (0.49) | ALDH1A1USP2TSHR | |
| SCHEMBL23259451 | 0.83 | LRRK2 (0.62) | LRRK2FAAHHTR1ASLC6A4SLC6A2 | |
| SCHEMBL2303266 | 0.80 | ALDH1A1 (0.61) | ALDH1A1USP2TSHRHSD17B10SIGMAR1 | |
| SCHEMBL7652198 | 0.79 | ACVR1 (0.47) | ALDH1A1SIGMAR1HTR1AHTR1BHTR3E | |
| Hydrochloric Acid SCHEMBL27216584 | 0.78 | KDM4E (0.49) | ALDH1A1SIGMAR1HTR1AHTR1BHTR6 | |
| SCHEMBL30872535 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TSHRHTR1ASLC6A4TDP1 | |
| SCHEMBL2766477 | 0.77 | HTR1A (0.59) | LRRK2SIGMAR1HTR1ASLC6A4SLC6A2 | |
| SCHEMBL31584090 | 0.76 | ACVR1 (0.45) | ALDH1A1USP2TSHRHSD17B10SIGMAR1 | |
| SCHEMBL31583358 | 0.76 | TMEM97 (0.53) | SIGMAR1TMEM97HTR1ASLC6A4ADRA2A | |
| SCHEMBL6832741 | 0.76 | TDP1 (0.59) | ALDH1A1TSHRTDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837870-A | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-17 | — | — | US | claimed |
| EP-1328509-A1 | METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS | Pharmacia & Upjohn Company (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032857-A1 | METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
| US-5837870-A | Process to prepare oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-17 | — | — | US | disclosed |