Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 7/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782817 | 1.00 | RORC (0.35) | RORCIDH1NAMPTMGLLCHIA | |
| SCHEMBL6831648 | 1.00 | RORC (0.35) | RORCIDH1NAMPTMGLLCHIA | |
| SCHEMBL7089116 | 0.93 | HTR1A (0.38) | RORCIDH1NAMPTTNFLMNA | |
| SCHEMBL6788834 | 0.93 | HTR1A (0.38) | RORCIDH1NAMPTTNFLMNA | |
| SCHEMBL6786463 | 0.93 | HTR1A (0.38) | RORCIDH1NAMPTTNFLMNA | |
| SCHEMBL6865714 | 0.92 | PPARA (0.34) | RORCIDH1NAMPTCHIACHI3L1 | |
| SCHEMBL6865711 | 0.92 | PPARA (0.34) | RORCIDH1NAMPTCHIACHI3L1 | |
| SCHEMBL6787669 | 0.88 | CCR1 (0.37) | IDH1NAMPTPPARA | |
| SCHEMBL6787665 | 0.88 | CCR1 (0.37) | IDH1NAMPTPPARA | |
| SCHEMBL6787766 | 0.85 | AOC3 (0.35) | IDH1NAMPTTNFPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-A1 | HYDROXAMIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087870-A1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |