Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786463 | 1.00 | HTR1A (0.38) | HTR1ADRD4HTR2ASLC6A4DRD3 | |
| SCHEMBL6788834 | 1.00 | HTR1A (0.38) | HTR1ADRD4HTR2ASLC6A4DRD3 | |
| SCHEMBL6782817 | 0.93 | RORC (0.35) | RORCIDH1LMNANAMPTTNF | |
| SCHEMBL7090855 | 0.93 | RORC (0.35) | RORCIDH1LMNANAMPTTNF | |
| SCHEMBL6831648 | 0.93 | RORC (0.35) | RORCIDH1LMNANAMPTTNF | |
| SCHEMBL6782024 | 0.92 | LMNA (0.34) | RORCIDH1LMNAPOLBNAMPT | |
| SCHEMBL6782020 | 0.92 | LMNA (0.34) | RORCIDH1LMNAPOLBNAMPT | |
| Hydrochloric Acid SCHEMBL7177099 | 0.88 | CYP3A4 (0.33) | IDH1LMNAPOLBNAMPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7177094 | 0.88 | CYP3A4 (0.33) | IDH1LMNAPOLBNAMPTSMN1; SMN2 | |
| SCHEMBL6781731 | 0.86 | TDO2 (0.40) | IDH1NAMPTKCNH2PPARADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-A1 | HYDROXAMIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087870-A1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |