Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIP | O00170 | 1/20 | 0.44 |
| ▸ | SGTA | O43765 | 1/20 | 0.44 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.44 |
| ▸ | STIP1 | P31948 | 1/20 | 0.44 |
| ▸ | PPP5C | P53041 | 1/20 | 0.44 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.44 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.44 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.44 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.44 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364074 | 0.76 | KMT2A (0.53) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL3451713 | 0.72 | ALDH1A1 (0.56) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL16993653 | 0.68 | AIP (0.44) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL16420837 | 0.68 | GAA (0.30) | MAPTHSD17B10GAAMAPK1 | |
| SCHEMBL11324603 | 0.65 | AIP (0.66) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL16781055 | 0.64 | POLB (0.55) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL1004648 | 0.64 | POLB (0.55) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL28919248 | 0.64 | POLB (0.39) | KMT2AALDH1A1MEN1GAAPOLB | |
| SCHEMBL5964595 | 0.63 | ALDH1A1 (0.31) | ALDH1A1MAPTKDM4EPOLBLMNA | |
| SCHEMBL1003996 | 0.62 | POLB (0.52) | AIPSGTATOMM70STIP1PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294707-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-03-26 | — | — | EP | claimed |
| WO-2001098290-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-27 | — | — | WO | claimed |