Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | AIP | O00170 | 1/20 | 0.47 |
| ▸ | SGTA | O43765 | 1/20 | 0.47 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.47 |
| ▸ | STIP1 | P31948 | 1/20 | 0.47 |
| ▸ | PPP5C | P53041 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831152 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL3497284 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL14364074 | 0.81 | KMT2A (0.53) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1622729 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1063435 | 0.77 | KDM4E (0.60) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL10633454 | 0.77 | GRM6 (0.60) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL3452499 | 0.75 | CYP1A2 (0.55) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL11639797 | 0.74 | GAA (0.58) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1622309 | 0.74 | FHIT (0.77) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28209357 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133129-A2 | NOVEL DIHYDROINDENO[1,2-C]PYRAZOLE-3-CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEVELOPMENTAL DISORDERS OR NEURODEGENERATIVE DISEASES, COMPRISING SAME | 한국화학연구원 | 2021-07-01 | — | — | WO | disclosed |
| EP-2041124-B1 | PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS | MSD OSS BV (NL) | 2013-06-26 | — | — | EP | disclosed |
| EP-2041124-B1 | PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS | MSD OSS BV (NL) | 2013-06-26 | — | — | EP | disclosed |
| US-7820707-B2 | Heterocyclic derivatives | N.V. ORGANON (NL) | 2010-10-26 | — | — | US | disclosed |
| US-7820707-B2 | Heterocyclic derivatives | N.V. ORGANON (NL) | 2010-10-26 | — | — | US | disclosed |
| US-7820707-B2 | Heterocyclic derivatives | N.V. ORGANON (NL) | 2010-10-26 | — | — | US | disclosed |
| EP-2041124-A1 | PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS | N.V. Organon (NL) | 2009-04-01 | — | — | EP | disclosed |
| US-20080255086-A1 | Heterocyclic Derivatives | N.V. ORGANON (NL) | 2008-10-16 | — | — | US | disclosed |
| US-20080255086-A1 | Heterocyclic Derivatives | N.V. ORGANON (NL) | 2008-10-16 | — | — | US | disclosed |
| US-20080255086-A1 | Heterocyclic Derivatives | N.V. ORGANON (NL) | 2008-10-16 | — | — | US | disclosed |
| WO-2008003452-A1 | PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS | N.V. ORGANON (NL) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008003452-A1 | PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS | N.V. ORGANON (NL) | 2008-01-10 | — | — | WO | disclosed |
| EP-0004931-B1 | USE OF DERIVATIVES OF FURAN AND THIOPHENE AS PLANT-GROWTH REGULATING AGENTS | BAYER AG (DE) | 1981-08-05 | — | — | EP | disclosed |
| US-4240820-A | Method of regulating the growth of plants | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255086-A1 | Heterocyclic Derivatives | GRIN2C, GRIN3A, GRIN1 | ALDH1A1 453/4885MAPT 449/4885LMNA 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.