SCHEMBL5964595

SCHEMBL5964595

Cc1sc(N(C)C(=O)O)c(C)c1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9391212 0.67 GAA (0.35) POLB
SCHEMBL16311870 0.62 GPR35 (0.50) ALDH1A1POLBRECQLLMNAMAPT
Hydrochloric Acid SCHEMBL11840917 0.58 ALDH1A1 (0.50) ALDH1A1LMNAMAPT
SCHEMBL10979495 0.58 ALDH1A1 (0.34) ALDH1A1KDM4E
Methyl Alcohol SCHEMBL28556277 0.58 ALDH1A1 (0.50) ALDH1A1LMNAMAPTKDM4E
SCHEMBL7343408 0.58 PTGDR2 (0.40) ALDH1A1POLBLMNAMAPTKDM4E
SCHEMBL28986106 0.58 GAA (0.43) ALDH1A1LMNAMAPT
SCHEMBL25472450 0.57 ALDH1A1 (0.40) ALDH1A1LMNAMAPTKDM4E
SCHEMBL455438 0.57 KMT2A (0.53) ALDH1A1POLBLMNAKDM4E
SCHEMBL8304526 0.57 POLB (0.52) ALDH1A1POLBRECQLLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649750-A2 Synergistic insecticidal mixtures based on chloronicotinyl insecticides Bayer CropScience AG (DE) 2006-04-26 EP claimed
EP-1649750-A2 Synergistic insecticidal mixtures based on chloronicotinyl insecticides Bayer CropScience AG (DE) 2006-04-26 EP disclosed
EP-0735814-B1 OIL IN WATER EMULSIONS CLARIANT GMBH (DE) 2002-10-30 EP disclosed
EP-0735815-B1 OIL IN WATER EMULSIONS CLARIANT GMBH (DE) 1998-08-12 EP disclosed
EP-0828421-A1 INSECTICIDES BAYER AG (DE) 1998-03-18 EP disclosed
WO-1996037105-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-28 WO disclosed
EP-0735814-A1 OIL IN WATER EMULSIONS HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-09 EP disclosed
EP-0735815-A1 OIL IN WATER EMULSIONS HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-09 EP disclosed
WO-1995017088-A1 OIL IN WATER EMULSIONS HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
WO-1995017087-A1 OIL IN WATER EMULSIONS HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
EP-0297207-A2 Oil-in-water emulsions and process for the preparation and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
EP-0163836-B1 PROCESS AND APPARATUS FOR THE PRODUCTION OF GRANULES BAYER AG (DE) 1988-10-12 EP disclosed
EP-0062181-B1 OIL-IN-WATER EMULSIONS, METHOD FOR THEIR PREPARATION AND USE BAYER AG (DE) 1985-06-05 EP disclosed
EP-0085376-A2 Water-dispersible or water-soluble granulates, process for preparing them and their use BAYER AG (DE) 1983-08-10 EP disclosed