SCHEMBL7091033

SCHEMBL7091033

C=C(C)C(=O)OCCCCC(C)(C)O[Si](CCCOC(=O)C(=C)C)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL192202 0.90 TSHR (0.50) TSHRPOLBAPEX1HTTTDP1
SCHEMBL12924012 0.81 TSHR (0.44) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6672453 0.77 TSHR (0.38) TSHRPOLBAPEX1HTTTDP1
SCHEMBL24519228 0.76 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL136591 0.76 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19019780 0.76 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL29772677 0.76 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6672456 0.75 TSHR (0.37) TSHRPOLBAPEX1HTTTDP1
SCHEMBL38658604 0.75 TSHR (0.35) TSHRTHRB
SCHEMBL6829110 0.75 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030013043-A1 Method for making lithographic printing plate FUJIFILM CORPORATION (JP) 2003-01-16 US disclosed