SCHEMBL192202

SCHEMBL192202

C=C(C)C(=O)OCCC[Si](OC(C)(C)C)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.43
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091033 0.90 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12924012 0.90 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6672453 0.85 TSHR (0.38) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6672456 0.83 TSHR (0.37) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31278365 0.82 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29772677 0.81 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5446210 0.81 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.81 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23437 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
Hydrogen Sulfide SCHEMBL329768 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344238-B2 Self-cleaning protective coatings for use with photovoltaic cells SOLYNDRA LLC (US) 2013-01-01 US claimed
US-20110000539-A1 Self-cleaning protective coatings for use with photovoltaic cells SOLYNDRA, INC. (US) 2011-01-06 US claimed
US-20100326495-A1 Self-cleaning protective coatings for use with photovoltaic cells SOLYNDRA, INC. (US) 2010-12-30 US claimed
US-20070017567-A1 Self-cleaning protective coatings for use with photovoltaic cells BARNES, CHRISTOPHER 2007-01-25 US claimed
WO-2007012026-A1 SELF-CLEANING COATINGS SOLYNDRA, INC. (US) 2007-01-25 WO claimed
US-5338877-A Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS CO., LTD. (JP) 1994-08-16 US claimed
US-20240122814-A1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2024-04-18 US disclosed
EP-4327798-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2024-02-28 EP disclosed
WO-2022224807-A1 DENTAL ADHESIVE COMPOSITION 株式会社トクヤマデンタル 2022-10-27 WO disclosed
EP-3142617-B1 PHOTORESPONSIVE POLYMERS FOR ADHESIVE APPLICATIONS UNIV AKRON (US) 2021-11-03 EP disclosed
US-10336923-B2 Photoresponsive polymers for adhesive applications THE UNIVERSITY OF AKRON (US) 2019-07-02 US disclosed
EP-2839968-B1 ORIGINAL PLATE FOR LITHOGRAPHIC PRINTING PLATE, AND METHOD FOR PRINTING SAME FUJIFILM CORP (JP) 2018-07-11 EP disclosed
US-20170081568-A1 PHOTORESPONSIVE POLYMERS FOR ADHESIVE APPLICATIONS THE UNIVERSITY OF AKRON 2017-03-23 US disclosed
EP-0487094-B1 Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OILS & FATS CO LTD (JP) 1996-01-31 EP disclosed
US-5414065-A Polymer comprising fluoroalkyl group, a method of preparation thereof, a surface active agent, a surface treatment agent and a coating composition NOF CORPORATION (JP) 1995-05-09 US disclosed
US-5338877-A Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS CO., LTD. (JP) 1994-08-16 US disclosed
US-5324803-A End groups derived from fluoroalkanoyl peroxide; oil and water repellent NOF CORPORATION (JP) 1994-06-28 US disclosed
US-5288891-A Reacting an unsaturated silicon compound and a perfluoralkyl peroxide; waterproofing; oil repellents; adhesion; optical lenses; mold release agents NIPPON OIL AND FATS CO. LTD. (JP) 1994-02-22 US disclosed
EP-0537669-A1 A polymer comprising fluoroalkyl group, a method of preparation thereof, a surface active agent, a surface treatment agent and a coating composition NOF CORPORATION (JP) 1993-04-21 EP disclosed
EP-0487094-A1 Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122814-A1 DENTAL ADHESIVE COMPOSITION ITGA1, ILK, CAD TSHR 4510/4885THRB 2160/4885POLB 1765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.