SCHEMBL7091189

SCHEMBL7091189

CCCCCC1=NC(CCCCC)CO1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 6/20 0.41
NOS1 P29475 5/20 0.41
ALDH1A1 P00352 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
NOS3 P29474 3/20 0.34
CYP1A2 P05177 1/20 0.34
SCN2A Q99250 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854852 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL7854308 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL7846606 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL7857240 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL7651855 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL7856874 0.98 ALDH1A1 (0.41) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL28581955 0.96 NOS2 (0.45) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL28581953 0.96 NOS2 (0.45) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL10616856 0.95 NOS2 (0.44) NOS2NOS1ALDH1A1TAAR1NOS3
SCHEMBL10491961 0.86 ALDH1A1 (0.34) NOS2NOS1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368154-B Polypeptides 诺维信公司 2023-02-03 CN disclosed
CN-115210371-A Carbohydrate binding module variants 诺维信公司 2022-10-18 CN disclosed
CN-115011417-A Detergent compositions comprising bacterial mannanase AB酶股份有限公司 2022-09-06 CN disclosed
CN-114929848-A Stable liquid boron-free enzyme compositions 诺维信公司 2022-08-19 CN disclosed
CN-114846128-A Cleaning compositions comprising disperse protein VIII 汉高股份有限及两合公司 2022-08-02 CN disclosed
CN-114829564-A Cleaning compositions comprising dispersible protein and carbohydrase 汉高股份有限及两合公司 2022-07-29 CN disclosed
CN-114829563-A Cleaning compositions comprising dispersed protein IX 汉高股份有限及两合公司 2022-07-29 CN disclosed
CN-114829562-A Cleaning compositions comprising dispersible protein VI 汉高股份有限及两合公司 2022-07-29 CN disclosed
CN-114634921-A Alpha-amylase variants and polynucleotides encoding same 诺维信公司 2022-06-17 CN disclosed
CN-110709498-B Detergent compositions comprising bacterial mannanase AB酶股份有限公司 2022-01-14 CN disclosed
CN-110869483-A Detergent compositions containing enzymes 罗地亚经营管理公司 2020-03-06 CN disclosed
CN-110777016-A Detergent compositions with lipase variants 诺维信公司 2020-02-11 CN disclosed
CN-110709498-A Detergent compositions comprising bacterial mannanase AB酶股份有限公司 2020-01-17 CN disclosed
WO-2014090918-A1 PROCESS FOR THE ENANTIOMERIC ENRICHMENT OF DIARYLOXAZOLINE DERIVATIVES NOVARTIS AG (CH) 2014-06-19 WO disclosed
US-6670307-B2 Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock HOECHST SCHERING AGREVO GMBH (DE) 2003-12-30 US disclosed
EP-1087967-B1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES BAYER CROPSCIENCE GMBH (DE) 2003-10-22 EP disclosed
US-20020068828-A1 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides BAYER CROPSCIENCE AG (DE) 2002-06-06 US disclosed
US-6265350-B1 CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES HOECHST SCHERING AGREVO GMBH (DE) 2001-07-24 US disclosed
EP-1087967-A1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES Aventis CropScience GmbH (DE) 2001-04-04 EP disclosed
WO-1999065901-A1 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES AVENTIS CROPSCIENCE GMBH (DE) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068828-A1 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides MT-CO1, OXA1L, MT-CO3 NOS2 1343/4885NOS1 513/4885ALDH1A1 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.