Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PGD | P52209 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810608 | 1.00 | TDP1 (0.60) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL11068081 | 0.87 | TDP1 (0.70) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL7150686 | 0.87 | TDP1 (0.70) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL7150537 | 0.87 | TDP1 (0.70) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL8651044 | 0.87 | TDP1 (0.70) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL7154494 | 0.87 | TDP1 (0.70) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL13615064 | 0.86 | TDP1 (0.62) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL8653297 | 0.85 | TDP1 (0.73) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL7148849 | 0.85 | TDP1 (0.73) | TDP1PGDPOLBMAPK1ABCB1 | |
| SCHEMBL7152465 | 0.85 | TDP1 (0.73) | TDP1PGDPOLBMAPK1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| EP-1989179-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-01-26 | — | — | EP | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
| EP-1989179-A1 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2008-11-12 | — | — | EP | disclosed |
| US-20080260651-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2008-10-23 | — | — | US | disclosed |
| WO-2007094683-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053142-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | TDP1 3211/4885PGD 2243/4885POLB 2876/4885 |
| US-20080260651-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | TDP1 2931/4885PGD 1372/4885POLB 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.