Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414946 | 0.81 | ALDH1A1 (0.70) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL7877446 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL16811748 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8805565 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8330910 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8804897 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CYP1A2NPSR1TSHRCA1 | |
| SCHEMBL7874932 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL17083920 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8804894 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP1A2NPSR1TSHRHTT | |
| SCHEMBL8804890 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP1A2NPSR1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330432-A2 | SUBSTITUTED ALKANOIC ACIDS | Aventis Pharma Limited (GB) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036553-A2 | SUBSTITUTED ALKANOIC ACIDS | AVENTIS PHARMA LIMITED (GB) | 2002-05-10 | — | — | WO | disclosed |