Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.71 |
| ▸ | ITGAV | P06756 | 14/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091035 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8323660 | 0.82 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL6951803 | 0.82 | ITGB3 (0.73) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL5486017 | 0.80 | ITGB3 (0.65) | ITGB3ITGAVITGA2BITGB5POLB | |
| SCHEMBL7037287 | 0.75 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7442340 | 0.73 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL7090937 | 0.73 | ITGB3 (0.69) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7917702 | 0.73 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8468930 | 0.73 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7080320 | 0.73 | MAPT (0.73) | TSHRMAPK10MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910563-B1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6008213-A | A INHIBITOR OF VITRONECTIN RECEPTOR AND FIBRINOGEN RECEPTOR; USEFUL FOR INHIBITING PLATELET AGGREGATION AND OSTEOPOROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |