Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.59 |
| ▸ | ITGAV | P06756 | 13/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091404 | 0.82 | ITGB3 (0.71) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL8328260 | 0.80 | ALDH1A1 (0.50) | ITGB3ITGAVKMT2APOLBMAPT | |
| SCHEMBL7442340 | 0.77 | ITGB3 (0.59) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL6951803 | 0.77 | ITGB3 (0.73) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL1789085 | 0.75 | SMN1; SMN2 (0.54) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL7917702 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL8468930 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7360585 | 0.74 | ITGB3 (0.72) | ITGB3ITGAVITGA2BTSHRMAPK10 | |
| SCHEMBL7080320 | 0.74 | MAPT (0.73) | TSHRMAPK10SMN1; SMN2KMT2APOLB | |
| SCHEMBL7333365 | 0.72 | ITGB3 (1.00) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | claimed |