Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088442 | 0.82 | F10 (0.47) | F10F2PRSS1CASP3SRC | |
| SCHEMBL5640985 | 0.80 | F2 (0.56) | F10F2PRSS1CASP3MME | |
| SCHEMBL3724402 | 0.80 | F2 (0.56) | F10F2PRSS1CASP3MME | |
| SCHEMBL9608921 | 0.79 | F10 (0.60) | F10F2PRSS1CASP3SRC | |
| SCHEMBL12525646 | 0.79 | MMP1 (0.55) | F10F2PRSS1CASP3SRC | |
| SCHEMBL12494289 | 0.79 | MMP1 (0.55) | F10F2PRSS1CASP3SRC | |
| SCHEMBL6984269 | 0.78 | F10 (0.54) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL21165916 | 0.77 | F2 (0.53) | F10F2PRSS1CASP3SRC | |
| SCHEMBL6982747 | 0.77 | F10 (0.57) | F10F2PRSS1 | |
| SCHEMBL203869 | 0.76 | F2 (0.59) | F10F2PRSS1CASP3MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |