Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.40 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.40 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.40 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091821 | 0.80 | PLA2G2A (0.41) | LMNAPLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL4874217 | 0.76 | ACKR3 (0.42) | LMNAKMT2ARAB9A | |
| SCHEMBL4876185 | 0.74 | ACKR3 (0.43) | LMNAL3MBTL1KMT2A | |
| SCHEMBL4873305 | 0.71 | PARP1 (0.40) | LMNASOAT2SOAT1KMT2AGRIA2 | |
| SCHEMBL4870511 | 0.67 | SOAT2 (0.42) | LMNACD274SOAT2SOAT1L3MBTL1 | |
| SCHEMBL4870307 | 0.66 | SOAT2 (0.41) | LMNACD274SOAT2SOAT1L3MBTL1 | |
| SCHEMBL21357017 | 0.65 | BCAT2 (0.59) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL4871334 | 0.65 | KMT2A (0.40) | LMNASOAT2SOAT1KMT2ARAB9A | |
| SCHEMBL4875904 | 0.65 | SOAT2 (0.39) | LMNASOAT2SOAT1L3MBTL1KMT2A | |
| SCHEMBL4876529 | 0.65 | KMT2A (0.39) | LMNASOAT2SOAT1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |