Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093394 | 0.87 | — | — | |
| SCHEMBL4838366 | 0.82 | — | — | |
| SCHEMBL6653643 | 0.80 | TRIM24 (0.45) | TRIM24TRIM33 | |
| SCHEMBL4730800 | 0.79 | — | — | |
| SCHEMBL7272667 | 0.78 | TRIM24 (0.48) | TRIM24TRIM33 | |
| SCHEMBL256748 | 0.75 | — | — | |
| SCHEMBL561522 | 0.75 | — | — | |
| SCHEMBL7094004 | 0.73 | — | — | |
| SCHEMBL20522941 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL29892386 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192163-B1 | DITHIEPINO 6,5-b]PYRIDINES, AND RELATED COMPOSITIONS AND METHODS | ORTHO MCNEIL PHARM INC (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020103376-A1 | Dithiepino[6,5-b]pyridines, and related compositions and methods | BULLINGTON JAMES L (US) | 2002-08-01 | — | — | US | disclosed |
| US-20020032332-A1 | Dithiepino[6,5-b]pyridines, and related compositions and methods | BULLINGTON JAMES L (US) | 2002-03-14 | — | — | US | disclosed |
| US-20020026051-A1 | Dithiepino [6,5-b]pyridines, and related compositions and methods | BULLINGTON JAMES L (US) | 2002-02-28 | — | — | US | disclosed |
| US-6291454-B1 | CALCIUM CHANNEL ANTAGONISTS WITH CARDIOVASCULAR, ANTIASTHINATIC AND ANTIBRONCHOCONSTRICTION ACTIVITY. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103376-A1 | Dithiepino[6,5-b]pyridines, and related compositions and methods | TRPV5, QDPR, TRPV6 | TRIM24 4071/4885TRIM33 4196/4885 |
| US-20020026051-A1 | Dithiepino [6,5-b]pyridines, and related compositions and methods | TRPV5, QDPR, TRPV6 | TRIM24 4071/4885TRIM33 4196/4885 |
| US-20020032332-A1 | Dithiepino[6,5-b]pyridines, and related compositions and methods | TRPV5, QDPR, TRPV6 | TRIM24 4071/4885TRIM33 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.