Biphenyl

Biphenyl

SCHEMBL709232

C.C1CCC(C2CCCCC2)CC1.C1CCC(C2CCCCC2)CC1.N=C=O.N=C=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
HSD11B1 P28845 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
MAPT P10636 1/20 0.30
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8160471 1.00 ALDH1A1 (0.50) ALDH1A1HSD11B1CES2CES1MAPT
Biphenyl SCHEMBL15309189 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
SCHEMBL11035602 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
Methane SCHEMBL28287894 0.97 ALDH1A1 (0.53) ALDH1A1
SCHEMBL5201533 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
SCHEMBL61560 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
Biphenyl SCHEMBL4048778 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
Biphenyl SCHEMBL8071601 0.97 ALDH1A1 (0.53) ALDH1A1HSD11B1CES2CES1MAPT
SCHEMBL21463233 0.94 ALDH1A1 (0.57) ALDH1A1
SCHEMBL28045522 0.94 ALDH1A1 (0.57) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140039119-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION 2014-02-06 US claimed
US-20100256296-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-10-07 US claimed
EP-4370573-A1 SILANE MODIFIED ALIPHATIC POLYUREA Evonik Operations GmbH (DE) 2024-05-22 EP disclosed
WO-2023285177-A1 SILANE MODIFIED ALIPHATIC POLYUREA EVONIK OPERATIONS GMBH (DE) 2023-01-19 WO disclosed
US-11071347-B2 Suspension membranes, footwear including the same, footwear components, and related methods S-Ride, LLC (US) 2021-07-27 US disclosed
US-11041043-B2 Polycarbamide resins for metal coating applications EVONIK OPERATIONS GMBH (DE) 2021-06-22 US disclosed
US-20200199485-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-10683424-B2 Low gloss, high solids polyurea coatings EVONIK OPERATIONS GMBH (DE) 2020-06-16 US disclosed
US-20190365032-A1 SUSPENSION MEMBRANES, FOOTWEAR INCLUDING THE SAME, FOOTWEAR COMPONENTS, AND RELATED METHODS S-Ride, LLC 2019-12-05 US disclosed
US-20190031814-A1 POLYCARBAMIDE RESINS FOR METAL COATING APPLICATIONS EVONIK DEGUSSA GMBH (DE) 2019-01-31 US disclosed
US-20120279640-A1 METHOD OF MAKING EROSION RESISTANT COATINGS HONTEK CORPORATION (US) 2012-11-08 US disclosed
US-8178205-B2 Matte topcoat airfoil coatings HONTEK CORPORATION (US) 2012-05-15 US disclosed
US-8124235-B2 Method of making matte airfoil coatings HONTEK CORPORATION (US) 2012-02-28 US disclosed
US-20100255279-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-10-07 US disclosed
US-20100256296-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-10-07 US disclosed
US-20100249295-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-09-30 US disclosed
US-7736745-B2 Abrasion resistant coatings HONTEK CORPORATION (US) 2010-06-15 US disclosed
US-20100104520-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION IN THE FORM OF AN OIL-IN-WATER OR WATER-IN-OIL-IN-WATER EMULSION COMPRISING A HEAT-INDUCED GELLING POLYMER, A WATER-MISCIBLE VOLATILE ORGANIC SOLVENT AND AN ORGANIC UV-SCREENING AGENT L'OREAL S.A. (FR) 2010-04-29 US disclosed
US-20100031969-A1 EYELASH MAKEUP AND/OR CARE ASSEMBLY L'OREAL (FR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104520-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION IN THE FORM OF AN OIL-IN-WATER OR WATER-IN-OIL-IN-WATER EMULSION COMPRISING A HEAT-INDUCED GELLING POLYMER, A WATER-MISCIBLE VOLATILE ORGANIC SOLVENT AND AN ORGANIC UV-SCREENING AGENT KRT18, CUTA, POLK ALDH1A1 1490/4885HSD11B1 1236/4885CES2 3461/4885
US-20100031969-A1 EYELASH MAKEUP AND/OR CARE ASSEMBLY KRT18, FLNA, F7 ALDH1A1 4379/4885HSD11B1 3604/4885CES2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.