SCHEMBL7092850

SCHEMBL7092850

COc1ccc2c(c1)C(C)(C)C(C)N2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.43
ALDH1A1 P00352 2/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
KDM4E B2RXH2 2/20 0.40
PDE7A Q13946 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NOX1 Q9Y5S8 1/20 0.38
NQO1 P15559 2/20 0.38
POR P16435 2/20 0.38
AKR1B1 P15121 1/20 0.38
PDE3B Q13370 2/20 0.37
PDE3A Q14432 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11372667 0.82 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL11513649 0.80 CYP2D6 (0.40) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL11514660 0.80 MAOA (0.44) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL11517416 0.79 ALDH1A1 (0.41) SNCAALDH1A1PDE7AMAPK1SMN1; SMN2
SCHEMBL11515721 0.76 CREBBP (0.53) KMT2AMEN1MAOAMAOBHTR2B
SCHEMBL24725924 0.75 MRGPRX2 (0.40)
SCHEMBL6539867 0.75 AR (0.38) MAPTKMT2AMEN1LMNAAKR1B1
SCHEMBL5460910 0.75 AR (0.47)
SCHEMBL11516036 0.74 SNCA (0.40) SNCAALDH1A1MAPTKMT2AMEN1
SCHEMBL11519345 0.74 SNCA (0.41) SNCAALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6128497-A None JP disclosed
EP-3744810-B1 FLUORESCENT DYE, PREPARATION METHOD THEREFOR AND USE THEREOF UNIV SHENZHEN (CN) 2022-06-01 EP disclosed
CN-109642148-B Color developing composition, lithographic printing plate precursor, method for producing lithographic printing plate, and compound 富士胶片株式会社 2022-02-11 CN disclosed
US-10889719-B2 Fluorescent dye, preparation method therefor and use thereof SHENZHEN UNIVERSITY (CN) 2021-01-12 US disclosed
EP-3744810-A1 FLUORESCENT DYE, PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen University (CN) 2020-12-02 EP disclosed
US-20200095425-A1 FLUORESCENT DYE, PREPARATION METHOD THEREFOR AND USE THEREOF SHENZHEN UNIVERSITY (CN) 2020-03-26 US disclosed
EP-2330680-B1 DYE FOR PHOTOELECTRIC CONVERSION ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT TDK CORP (JP) 2013-10-23 EP disclosed
WO-2003092643-A1 LIGHT-PROTECTION FORMULATIONS USING ACRYLONITRILE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2003-11-13 WO disclosed
JP-H06128497-A FLUORAN COMPOUND AND ITS PRODUCTION FUJI PHOTO FILM CO LTD 1994-05-10 JP disclosed
US-5047539-A Ultraviolet radiation stabilizers BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0399278-A2 Heterocyclic amidine derivatives BASF Aktiengesellschaft (DE) 1990-11-28 EP disclosed
US-4792609-A SUNSCREEN AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1988-12-20 US disclosed
EP-0207287-A2 Indole derivatives, process for their preparation and cosmetic preparation containing them BAYER AG (DE) 1987-01-07 EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
EP-0002721-B1 PROCESS FOR PREPARING HYDRAZINES BAYER AG (DE) 1981-09-02 EP disclosed
US-4145537-A BENZOTHIAZOLIUM DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4017484-A Cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-04-12 US disclosed