Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10379868 | 0.80 | PRKCA (0.44) | PRKCA | |
| SCHEMBL12592739 | 0.80 | PRKCA (0.48) | PRKCACA2CA1MAPK1SLC1A3 | |
| SCHEMBL31112628 | 0.79 | PRKCA (0.47) | PRKCA | |
| SCHEMBL11335037 | 0.78 | CA2 (0.41) | PRKCACA2CA1MAPK1SLC1A3 | |
| SCHEMBL21811641 | 0.78 | ALDH1A1 (0.41) | PRKCACA2CA1MAPK1MAPT | |
| SCHEMBL29707924 | 0.73 | PRKCA (0.46) | PRKCACA2MAPK1MAPTPRSS1 | |
| SCHEMBL29707925 | 0.73 | PRKCA (0.46) | PRKCACA2MAPK1MAPTPRSS1 | |
| SCHEMBL29707920 | 0.73 | PRKCA (0.46) | PRKCACA2MAPK1MAPTPRSS1 | |
| SCHEMBL29707923 | 0.73 | PRKCA (0.46) | PRKCACA2MAPK1MAPTPRSS1 | |
| SCHEMBL594327 | 0.73 | PRKCA (0.46) | PRKCACA2MAPK1MAPTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084532-A1 | LIPOIC ACID ANALOGS USEFUL AS PROVITAMINS AND ANTIOXIDANTS | AVERY MITCHELL A (US) | 2003-10-16 | — | — | WO | disclosed |