SCHEMBL7092910

SCHEMBL7092910

c1cncc(-c2nccnc2-c2cccnc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 12/20 0.67
CYP3A4 P08684 4/20 0.67
ALDH1A1 P00352 2/20 0.67
CYP1A2 P05177 1/20 0.67
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
HTT P42858 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
IDO1 P14902 1/20 0.50
LRRK2 Q5S007 1/20 0.50
TDO2 P48775 1/20 0.50
CDK5 Q00535 1/20 0.50
CDK5R1 Q15078 1/20 0.50
CYP11B1 P15538 1/20 0.49
CYP11B2 P19099 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27893934 0.85 CYP2A6 (0.56) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL18818721 0.85 CYP2A6 (0.67) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL29890067 0.85 CYP2A6 (0.56) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL30206207 0.85 CYP2A6 (0.56) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL30032 0.82 PTGS2 (0.64) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL28181896 0.82 PTGS2 (0.64) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL31635952 0.82 PTGS2 (0.64) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL13910994 0.82 CYP2A6 (0.70) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL30473120 0.81 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL29419014 0.81 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170125700-A1 COMPOUND HAVING TETRAAZATRIPHENYLENE RING STRUCTURE, LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2017-05-04 US disclosed
US-20170125700-A1 COMPOUND HAVING TETRAAZATRIPHENYLENE RING STRUCTURE, LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2017-05-04 US disclosed
US-6555308-B1 Silver halide particles containing a polynuclear metal complex in which an organic compound is contained as a bridging ligand; high contrast, photosensitivity and good graininess; high speed forming a color image FUJI PHOTO FILM CO., LTD. (JP) 2003-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170125700-A1 COMPOUND HAVING TETRAAZATRIPHENYLENE RING STRUCTURE, LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE LEF1, TEAD1, LAGE3 CYP2A6 1803/4885CYP3A4 167/4885ALDH1A1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.