Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 11/20 | 0.54 |
| ▸ | GRPR | P30550 | 10/20 | 0.54 |
| ▸ | FPR1 | P21462 | 6/20 | 0.54 |
| ▸ | FPR2 | P25090 | 6/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253303 | 0.92 | NMBR (0.62) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6810086 | 0.92 | NMBR (0.62) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6253532 | 0.86 | NMBR (0.58) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6810082 | 0.85 | NMBR (0.72) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6252249 | 0.85 | NMBR (0.72) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6251562 | 0.83 | NMBR (0.63) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6251350 | 0.81 | FPR1 (0.43) | NMBRGRPRFPR1FPR2 | |
| SCHEMBL7092917 | 0.81 | FPR1 (0.37) | NMBRGRPRFPR1FPR2 | |
| SCHEMBL6255724 | 0.80 | NMBR (0.67) | NMBRGRPRFPR1FPR2AGTR1 | |
| SCHEMBL6254936 | 0.74 | NMBR (0.55) | NMBRGRPRFPR1FPR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334102-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040475-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | disclosed |