Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 4/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NMBR | P28336 | 3/20 | 0.36 |
| ▸ | GRPR | P30550 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253307 | 0.92 | TACR1 (0.41) | FPR1FPR2TACR1TP53POLB | |
| SCHEMBL6253540 | 0.87 | NMBR (0.38) | FPR1FPR2TACR1TP53POLB | |
| SCHEMBL6252251 | 0.85 | NMBR (0.48) | FPR1TACR1NMBRGRPR | |
| SCHEMBL6252419 | 0.83 | TACR1 (0.40) | FPR1FPR2TACR1NMBRGRPR | |
| SCHEMBL6251353 | 0.81 | MEN1 (0.35) | MMP2KMT2A | |
| SCHEMBL7092916 | 0.81 | NMBR (0.54) | FPR1FPR2NMBRGRPR | |
| SCHEMBL7636672 | 0.80 | GHSR (0.44) | FPR1FPR2TACR1TP53POLB | |
| SCHEMBL6718194 | 0.80 | GHSR (0.44) | FPR1FPR2TACR1TP53POLB | |
| SCHEMBL6251031 | 0.74 | ALDH1A1 (0.37) | FPR1MAPTNMBRGRPRKMT2A | |
| SCHEMBL6994303 | 0.74 | ALDH1A1 (0.37) | FPR1MAPTNMBRGRPRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334102-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040475-A1 | BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | disclosed |