Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670969 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL8326095 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| Hydrochloric Acid SCHEMBL7645327 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL6716017 | 0.81 | L3MBTL1 (0.45) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL8421338 | 0.81 | PTGS2 (0.48) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL7772904 | 0.76 | KMT2A (0.37) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL8325647 | 0.76 | KMT2A (0.40) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL9829521 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1HSP90AA1KMT2AMEN1 | |
| SCHEMBL8321067 | 0.73 | POLB (0.47) | KDM4EALDH1A1POLBTP53HSP90AA1 | |
| SCHEMBL2164198 | 0.72 | PTGS2 (0.46) | KDM4EALDH1A1POLBTP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003075910-A1 | PREVENTING AND/OR TREATING VASCULAR DISEASE, CARDIOMYOPATHY AND/OR ASSOCIATED HEART FAILURE | PROTEMIX CORPORATION LIMITED (NZ) | 2003-09-18 | — | — | WO | claimed |