Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.44 |
| ▸ | FNTB | P49356 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090215 | 0.85 | FNTA (0.48) | FNTAFNTBRORCPGGT1BIDO1 | |
| SCHEMBL7095411 | 0.76 | FNTA (0.41) | FNTAFNTBRORCPGGT1BIDO1 | |
| SCHEMBL7166191 | 0.75 | RORC (0.42) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL7643836 | 0.75 | FNTA (0.47) | FNTAFNTBRORCPGGT1BIDO1 | |
| SCHEMBL7195141 | 0.75 | FNTA (0.47) | FNTAFNTBRORCPGGT1BIDO1 | |
| SCHEMBL5016765 | 0.75 | FNTA (0.46) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL6987223 | 0.75 | IDO1 (0.48) | FNTAFNTBRORCIDO1 | |
| SCHEMBL7094552 | 0.75 | IDO1 (0.48) | FNTAFNTBRORCIDO1 | |
| SCHEMBL16632803 | 0.74 | RORC (0.59) | RORC | |
| SCHEMBL6009561 | 0.72 | FNTA (0.49) | FNTAFNTBPGGT1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322635-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024682-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |