SCHEMBL709318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL709317	0.90	MCL1 (0.47)	PLA2G4AHPGDMEN1KMT2APOLB
	SCHEMBL705825	0.87	SRD5A2 (0.57)	HPGDMEN1KMT2APOLBALDH1A1
	SCHEMBL706447	0.77	LPAR1 (0.52)	HPGDMEN1KMT2APOLBALDH1A1
	SCHEMBL706891	0.75	KMT2A (0.42)	HPGDMEN1KMT2APOLBALDH1A1
	SCHEMBL8761239	0.73	GRIK1 (0.54)	ALDH1A1
	SCHEMBL708944	0.73	LPAR1 (0.52)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL708379	0.72	POLB (0.51)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL707824	0.72	LPAR1 (0.52)	—
	SCHEMBL13802519	0.71	SRD5A2 (0.72)	PLA2G4AMEN1KMT2ALTB4RLTB4R2
	SCHEMBL2015584	0.70	SRD5A2 (0.63)	PLA2G4AMEN1KMT2ALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.