Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093257 | 1.00 | MAPT (0.39) | MAPTPOLBMAPK1IDO1L3MBTL1 | |
| SCHEMBL7141370 | 0.83 | NPFFR1 (0.40) | MAPTPOLBMAPK1L3MBTL1CA1 | |
| SCHEMBL4040006 | 0.80 | CA12 (0.47) | MAPTPOLBMAPK1IDO1L3MBTL1 | |
| SCHEMBL7092445 | 0.77 | NPFFR1 (0.39) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL7089757 | 0.77 | CA2 (0.44) | CA1CA2CA12CA9LMNA | |
| SCHEMBL7089756 | 0.77 | CA2 (0.44) | CA1CA2CA12CA9LMNA | |
| SCHEMBL7093260 | 0.76 | CA2 (0.35) | POLBCA1CA2CA12CA9 | |
| SCHEMBL4038788 | 0.74 | STK17B (0.50) | IDO1CA1CA2CYP1A1CYP2D6 | |
| SCHEMBL18656008 | 0.72 | SIGMAR1 (0.48) | MAPTPOLBMAPK1IDO1L3MBTL1 | |
| SCHEMBL13622021 | 0.71 | IDO1 (0.56) | MAPTPOLBMAPK1IDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |