Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292846 | 0.83 | TSHR (0.41) | MEN1KMT2A | |
| SCHEMBL6256220 | 0.80 | CYP1A2 (0.35) | MEN1KMT2A | |
| SCHEMBL18757583 | 0.79 | CXCR4 (0.38) | — | |
| SCHEMBL11361526 | 0.79 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL11684387 | 0.77 | CYP1A2 (0.46) | — | |
| SCHEMBL6448611 | 0.75 | — | — | |
| SCHEMBL11460652 | 0.74 | KCNH3 (0.43) | KMT2A | |
| SCHEMBL6511999 | 0.72 | KMT2A (0.38) | MEN1KMT2A | |
| SCHEMBL9021224 | 0.72 | SMN1; SMN2 (0.43) | MEN1KMT2A | |
| SCHEMBL9526292 | 0.72 | TSHR (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341773-A2 | SUBSTITUTED 1,3,5-TRIAZINES AND PYRIMIDINES AS ABCA-1 ELEVATING COMPOUNDS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046172-A2 | SUBSTITUTED 1, 3, 5-TRIAZINES AND PYRIMIDINES AS ABCA-1 ELEVATING COMPOUNDS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2002-06-13 | — | — | WO | disclosed |