Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.49 |
| ▸ | AKT1 | P31749 | 3/20 | 0.49 |
| ▸ | NEK4 | P51957 | 3/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.49 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.49 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.49 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848822 | 0.80 | ROCK2 (0.70) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL2777735 | 0.80 | ROCK2 (0.70) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL9293287 | 0.80 | ROCK2 (0.70) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL4660820 | 0.78 | KDM4E (0.67) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL5642916 | 0.78 | KDM4E (0.67) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL22995641 | 0.78 | MEN1 (0.61) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL3717471 | 0.78 | MEN1 (0.61) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL9848486 | 0.78 | RPS6KA5 (0.71) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL4659439 | 0.78 | KDM4E (0.67) | KDM4EGAAMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29693063 | 0.78 | GSK3B (0.68) | KDM4EGAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |