Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370948 | 0.82 | ALDH1A1 (0.48) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL8048603 | 0.81 | ALDH1A1 (0.61) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL23611750 | 0.81 | ALDH1A1 (0.47) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL8097591 | 0.78 | OPRL1 (0.58) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL29467270 | 0.78 | NPC1 (0.68) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL2492855 | 0.78 | NPC1 (0.68) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL1715918 | 0.76 | NPC1 (0.71) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL227731 | 0.76 | NPC1 (0.71) | POLBNPC1ALDH1A1ALOX15MYC | |
| SCHEMBL2952285 | 0.75 | KDM4E (0.51) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL3808106 | 0.75 | ALDH1A1 (0.70) | POLBNPC1ALDH1A1ALOX15MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |