Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734017 | 0.85 | BCAT2 (0.42) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL1227194 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRKDM4EHPGD | |
| SCHEMBL27863652 | 0.83 | BCAT2 (0.47) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL10992096 | 0.82 | SIRT1 (0.46) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL2762268 | 0.81 | MAPT (0.46) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL3644388 | 0.81 | NPSR1 (0.47) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL7259310 | 0.80 | ALDH1A1 (0.44) | BCAT2ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL31179917 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTTSHRKDM4EPOLB | |
| SCHEMBL13587852 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRKDM4EHPGD | |
| SCHEMBL21808781 | 0.78 | AKR1C3 (0.53) | ALDH1A1MAPTTSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |