Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514293 | 0.86 | LMNA (0.33) | LMNAESR1MAPT | |
| SCHEMBL4505114 | 0.77 | KDM4E (0.35) | — | |
| Hydrochloric Acid SCHEMBL7099684 | 0.76 | PIM1 (0.45) | LMNA | |
| SCHEMBL4505813 | 0.72 | TOP2A (0.39) | — | |
| SCHEMBL12835810 | 0.69 | EEF2K (0.41) | LMNAMAPT | |
| SCHEMBL4515223 | 0.69 | ALDH1A1 (0.38) | MAPT | |
| SCHEMBL4514575 | 0.69 | ALDH1A1 (0.36) | LMNA | |
| Hydrochloric Acid SCHEMBL6694577 | 0.68 | PIM1 (0.44) | LMNA | |
| SCHEMBL6647130 | 0.68 | EEF2K (0.37) | — | |
| SCHEMBL12836318 | 0.68 | EEF2K (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | ABCC1, RPS6KA1, SIGMAR1 | LMNA 3614/4885ESR1 4021/4885MAPT 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.