Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095147 | 0.93 | CYP1A2 (0.56) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL9698379 | 0.91 | TSHR (0.51) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL17090762 | 0.91 | LMNA (0.57) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL6766000 | 0.90 | LMNA (0.52) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL17885932 | 0.86 | CYP1A2 (0.50) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL32670803 | 0.83 | PTPN11 (0.57) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL6757271 | 0.83 | PTPN11 (0.57) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL12697311 | 0.83 | CYP1A2 (0.51) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| Hexadecane SCHEMBL28894271 | 0.83 | TSHR (0.68) | TSHRLMNAALDH1A1CYP3A4TP53 | |
| SCHEMBL9305910 | 0.83 | LMNA (0.70) | TSHRLMNAALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144458-A1 | Novel amphiphilic polymeric materials | UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION | 2003-07-31 | — | — | US | disclosed |
| US-6521736-B2 | Can be used in development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems e.g., for delivery of anti-HIV or anticancer drugs | UNIVERSITY OF MASSACHUSETTS | 2003-02-18 | — | — | US | disclosed |
| US-20020099164-A1 | Novel amphiphilic polymeric materials | UNIVERSITY OF MASSACHUSETTS | 2002-07-25 | — | — | US | disclosed |