Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684319 | 0.88 | MAPT (0.77) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL1011945 | 0.88 | HSD17B2 (0.61) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL23876967 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL21079240 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL7089045 | 0.85 | TSHR (0.65) | ALDH1A1MAPTMAPK1TSHRCA12 | |
| SCHEMBL16605589 | 0.85 | MAPT (0.57) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL6066522 | 0.84 | CA12 (0.64) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL9005554 | 0.84 | HSD17B2 (0.70) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL3201517 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1HSD17B2TSHR | |
| SCHEMBL16605593 | 0.82 | MAPT (0.55) | ALDH1A1MAPTMAPK1HSD17B2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | ALDH1A1 1023/4885MAPT 3795/4885MAPK1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.