Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839016 | 1.00 | CHRNA7 (0.56) | CHRNA7KCNH2PARP1HRH3HTR3E | |
| SCHEMBL4847239 | 0.81 | CHRNA7 (0.46) | CHRNA7KCNH2PARP1KDM4E | |
| SCHEMBL4846555 | 0.76 | ALDH1A1 (0.51) | CHRNA7KCNH2PARP1HTR3EHTR3B | |
| SCHEMBL4845936 | 0.74 | KDM4E (0.45) | CHRNA7KCNH2PARP1KDM4EALDH1A1 | |
| SCHEMBL18081170 | 0.74 | CHRNA7 (0.63) | CHRNA7KCNH2PARP1 | |
| SCHEMBL4839072 | 0.73 | CSNK1E (0.49) | PARP1 | |
| SCHEMBL4109510 | 0.71 | CHRNA7 (1.00) | CHRNA7KCNH2 | |
| SCHEMBL4109513 | 0.71 | CHRNA7 (1.00) | CHRNA7KCNH2 | |
| SCHEMBL6627648 | 0.71 | CHRNA7 (1.00) | CHRNA7KCNH2 | |
| SCHEMBL4109514 | 0.71 | CHRNA7 (1.00) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368348-A1 | NOVEL 2,5-DIAZABICYCLO(2.2.1)HEPTANE DERIVATIVES | NEUROSEARCH A/S (DK) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070522-A1 | NOVEL 2,5-DIAZABICYCLO[2.2.1]HEPTANE DERIVATIVES | NEUROSEARCH A/S (DK) | 2002-09-12 | — | — | WO | disclosed |