Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961934 | 0.89 | LPAR1 (0.46) | LPAR1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL7960296 | 0.86 | LPAR1 (0.50) | LPAR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7950092 | 0.81 | MAPK1 (0.53) | LPAR1ALDH1A1MAPK1MME | |
| SCHEMBL7949664 | 0.80 | NPSR1 (0.45) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2063733 | 0.77 | LPAR1 (0.50) | LPAR1NPC1RAB9A | |
| SCHEMBL7960040 | 0.76 | LPAR1 (0.48) | LPAR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7960940 | 0.74 | LPAR1 (0.48) | LPAR1NPC1RAB9AGPR139KMT2A | |
| SCHEMBL8701833 | 0.73 | LPAR1 (0.46) | LPAR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7961796 | 0.73 | LPAR1 (0.45) | LPAR1MEN1KMT2A | |
| SCHEMBL1424025 | 0.72 | ACHE (0.47) | LPAR1ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |