Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960120 | 0.84 | SMN1; SMN2 (0.45) | LPAR1 | |
| SCHEMBL8960117 | 0.84 | SMN1; SMN2 (0.45) | LPAR1 | |
| SCHEMBL1814210 | 0.83 | ACHE (0.46) | LPAR1ACHENPC1RAB9A | |
| SCHEMBL3149952 | 0.82 | MEN1 (0.41) | NPC1RAB9A | |
| SCHEMBL16219339 | 0.80 | MT-CO2 (0.41) | — | |
| SCHEMBL28968846 | 0.79 | POLB (0.43) | — | |
| SCHEMBL7960296 | 0.79 | LPAR1 (0.50) | LPAR1NPC1RAB9A | |
| SCHEMBL5541713 | 0.79 | LPAR1 (0.49) | LPAR1ACHE | |
| SCHEMBL10174511 | 0.79 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL11069259 | 0.78 | MT-CO2 (0.49) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062884-B1 | Phenylacetic acid derivatives and pharmaceutical composition thereof | FUJI YAKUHIN CO LTD (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8148421-B2 | Phenylacetic acid derivative | FUJI YAKUHIN CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2062884-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
| US-6569810-B1 | (2-alkoxycarbonylcyclohexyl) (substituted benzyl) ketones of given formula; insecticidal, acaricidal and herbicidal action | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-27 | — | — | US | disclosed |
| US-6515184-B1 | The present invention relates to novel bicyclic cyclopentane-1,3- dione derivatives of the formula (I) to a process for their preparation and to their use as pesticides and herbicides. | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | PTGS1, PTGER1, PTGDR | LPAR1 792/4885ACHE 4109/4885NPC1 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.