Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960040 | 0.90 | LPAR1 (0.48) | LPAR1GPR139NPC1RAB9AKMT2A | |
| SCHEMBL7957895 | 0.84 | LPAR1 (0.46) | LPAR1GPR139NPC1RAB9AKMT2A | |
| SCHEMBL7959929 | 0.83 | LPAR1 (0.43) | LPAR1GPR139NPC1RAB9AKMT2A | |
| SCHEMBL7957914 | 0.83 | TAS1R3 (0.44) | LPAR1GPR139NPC1RAB9AKMT2A | |
| SCHEMBL7960618 | 0.79 | SCN1A (0.41) | RAB9AKMT2A | |
| SCHEMBL8701833 | 0.79 | LPAR1 (0.46) | LPAR1NPC1RAB9AKMT2A | |
| SCHEMBL7964513 | 0.78 | LPAR1 (0.43) | LPAR1NPC1RAB9A | |
| SCHEMBL7958367 | 0.78 | LPAR1 (0.43) | LPAR1GPR139NPC1RAB9AKMT2A | |
| SCHEMBL2063733 | 0.77 | LPAR1 (0.50) | LPAR1NPC1RAB9A | |
| SCHEMBL7960296 | 0.76 | LPAR1 (0.50) | LPAR1GPR139NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |