Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.34 |
| ▸ | MMP3 | P08254 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050596 | 0.81 | MMP2 (0.34) | MMP1MMP3KMT2AMMP2MMP7 | |
| SCHEMBL10268571 | 0.79 | MMP1 (0.39) | MMP1MMP3KAT2BDPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15124307 | 0.77 | MMP1 (0.39) | MMP1MMP3KAT2BDPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL319091 | 0.77 | MMP1 (0.39) | MMP1MMP3KAT2BDPP4ALDH1A1 | |
| SCHEMBL823276 | 0.75 | PIK3CD (0.50) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6522401 | 0.74 | MMP1 (0.43) | MMP1MMP3DPP4ALDH1A1PARP1 | |
| SCHEMBL10264904 | 0.74 | KMT2A (0.44) | MEN1KMT2ARAB9APOLB | |
| SCHEMBL14275858 | 0.73 | BRD4 (0.46) | DPP4 | |
| Hydrochloric Acid SCHEMBL15124168 | 0.73 | MMP1 (0.43) | MMP1MMP3DPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15124169 | 0.73 | MMP1 (0.43) | MMP1MMP3DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0815084-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029313-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |