Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028361 | 0.94 | LMNA (0.40) | LMNAMETAP1TSHR | |
| SCHEMBL598055 | 0.94 | LMNA (0.40) | LMNAMETAP1TSHR | |
| SCHEMBL599589 | 0.91 | LMNA (0.42) | LMNAMETAP1TSHR | |
| SCHEMBL18933350 | 0.85 | TSHR (0.36) | LMNAMETAP1TSHR | |
| SCHEMBL2338438 | 0.84 | LMNA (0.34) | LMNAMETAP1 | |
| SCHEMBL1404786 | 0.82 | LMNA (0.48) | LMNAMETAP1TSHR | |
| SCHEMBL2503665 | 0.81 | ALDH1A1 (0.37) | LMNATSHR | |
| SCHEMBL3386897 | 0.81 | LMNA (0.36) | LMNAMETAP1TSHR | |
| SCHEMBL3438064 | 0.81 | ALDH1A1 (0.37) | LMNAMETAP1TSHR | |
| SCHEMBL10958918 | 0.81 | LMNA (0.36) | LMNAMETAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | DERA, DPYD, DHPS | LMNA 2068/4885METAP1 1730/4885TSHR 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.