Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094272 | 0.83 | ABCG2 (0.40) | ALDH1A1CYP2A6TDP1KDM4ECYP1A2 | |
| SCHEMBL29748869 | 0.82 | ALDH1A1 (0.38) | HSD17B10ALDH1A1CYP2A6TSHRTDP1 | |
| SCHEMBL6924821 | 0.80 | HTR7 (0.39) | HSD17B10ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL29749091 | 0.76 | ALDH1A1 (0.39) | HSD17B10ALDH1A1CYP2A6TSHRTDP1 | |
| SCHEMBL3056466 | 0.74 | ALDH1A1 (0.41) | HSD17B10ALDH1A1CYP2A6TSHRTDP1 | |
| Lithium SCHEMBL29650601 | 0.73 | CYP2A6 (0.39) | HSD17B10ALDH1A1CYP2A6TSHRTDP1 | |
| SCHEMBL5657362 | 0.72 | WDR5 (0.43) | HSD17B10ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL28348030 | 0.71 | ALDH1A1 (0.38) | HSD17B10ALDH1A1CYP2A6TSHRTDP1 | |
| SCHEMBL6926322 | 0.70 | PRCP (0.42) | HSD17B10ALDH1A1CYP2A6HPGDANPEP | |
| SCHEMBL1673285 | 0.69 | KDM4E (0.33) | HSD17B10KDM4ECYP1A2GLACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| CN-1228072-A | Process for preparing 2-aryl-substituted indenes | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-09-08 | — | — | CN | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |