Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30196993 | 1.00 | MAPKAPK2 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3EGLN1 | |
| SCHEMBL30297094 | 0.82 | MAPKAPK2 (0.40) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL21530547 | 0.81 | PARP1 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3EGLN1 | |
| SCHEMBL30196908 | 0.81 | PARP1 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3EGLN1 | |
| SCHEMBL30212575 | 0.78 | MAPKAPK2 (0.37) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL707250 | 0.74 | EGLN1 (0.40) | MAPKAPK2RPS6KA3CSNK2A1PLK3EGLN1 | |
| SCHEMBL16671449 | 0.70 | MAPKAPK2 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL704132 | 0.70 | MAPKAPK2 (0.39) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL29961305 | 0.68 | LMNA (0.42) | ALDH1A1HRH4KDM4ELMNAMEN1 | |
| SCHEMBL1171365 | 0.68 | HRH4 (0.44) | EGLN1HRH4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11219214-B2 | Benzosultams and analogues and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-01-11 | — | — | US | claimed |
| US-20200323211-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-15 | — | — | US | claimed |
| US-20190335753-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-11-07 | — | — | US | claimed |
| EP-3604288-B1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | DEV CT BIOTECHNOLOGY (TW) | 2024-04-10 | — | — | EP | disclosed |
| EP-3478659-B1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11219214-B2 | Benzosultams and analogues and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-01-11 | — | — | US | disclosed |
| CN-110790713-B | Regioselective one-step process for the synthesis of 2-hydroxyquinoxaline | 财团法人生物技术开发中心 | 2021-03-05 | — | — | CN | disclosed |
| US-20200323211-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-15 | — | — | US | disclosed |
| US-10736321-B2 | Benzosultams and analogues and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-08-11 | — | — | US | disclosed |
| CN-110790713-A | Regioselective one-step process for the synthesis of 2-hydroxyquinoxaline | 财团法人生物技术开发中心 | 2020-02-14 | — | — | CN | disclosed |
| EP-3604288-A1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | Development Center for Biotechnology (TW) | 2020-02-05 | — | — | EP | disclosed |
| US-20190335753-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-11-07 | — | — | US | disclosed |
| US-20120108577-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2012-05-03 | — | — | US | disclosed |
| US-8124602-B2 | Compounds for the treatment of multi-drug resistant bacterial infections | ASTRAZENECA AB (SE) | 2012-02-28 | — | — | US | disclosed |
| US-20110092495-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2011-04-21 | — | — | US | disclosed |
| EP-2289890-A1 | Compounds for the treatment of multi-drug resistant bacterial infections | AstraZeneca AB (SE) | 2011-03-02 | — | — | EP | disclosed |
| US-7875715-B2 | 6-[({1-[2-(7-methoxy-2-oxoquinoxalin-1(2H)-yl)ethyl]piperidin-4-yl}amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one; antibacteria; methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), penicillin-resistant Streptococcus pneumoniae | ASTRAZENECA AB (SE) | 2011-01-25 | — | — | US | disclosed |
| US-20100152441-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | US | disclosed |
| EP-1893599-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134378-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323211-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | GABBR1, DPM1, CYP51A1 | MAPKAPK2 1821/4885RPS6KA3 3059/4885CSNK2A1 4082/4885 |
| US-10736321-B2 | Benzosultams and analogues and their use as fungicides | GABBR1, DPM1, CYP51A1 | MAPKAPK2 1821/4885RPS6KA3 3059/4885CSNK2A1 4082/4885 |
| US-20110092495-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | PIGS, BPGM, IPMK | MAPKAPK2 3825/4885RPS6KA3 1899/4885CSNK2A1 4226/4885 |
| US-20120108577-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | PIGS, BPGM, IPMK | MAPKAPK2 3825/4885RPS6KA3 1899/4885CSNK2A1 4226/4885 |
| US-20190335753-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | GABBR1, DPM1, CYP51A1 | MAPKAPK2 1821/4885RPS6KA3 3059/4885CSNK2A1 4082/4885 |
| US-11219214-B2 | Benzosultams and analogues and their use as fungicides | GABBR1, DPM1, CYP51A1 | MAPKAPK2 1821/4885RPS6KA3 3059/4885CSNK2A1 4082/4885 |
| US-20100152441-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | PIGS, BPGM, IPMK | MAPKAPK2 3825/4885RPS6KA3 1899/4885CSNK2A1 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.