Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094711 | 0.78 | TSHR (0.35) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL236431 | 0.64 | TSHR (0.56) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL4600179 | 0.61 | TSHR (0.52) | TSHRMEN1KMT2AGSK3AGSK3B | |
| Ethylene Glycol SCHEMBL27986613 | 0.60 | TSHR (0.50) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL10204473 | 0.58 | TSHR (0.41) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL21152154 | 0.57 | CA12 (0.52) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL1063100 | 0.57 | TSHR (0.43) | TSHRMEN1KMT2AGSK3AGSK3B | |
| Succinimide SCHEMBL27157818 | 0.57 | TSHR (0.43) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL1055378 | 0.57 | TSHR (0.43) | TSHRMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL515800 | 0.57 | PTGS1 (0.52) | TSHRMEN1KMT2AGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294698-A1 | FUSED AZEPINE DERIVATIVES AND THEIR USE AS ANTIDIURETIC AGENTS | FERRING B.V. (NL) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000626-A1 | FUSED AZEPINE DERIVATIVES AND THEIR USE AS ANTIDIURETIC AGENTS | FERRING B.V. (NL) | 2002-01-03 | — | — | WO | disclosed |