Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515800 | 0.84 | PTGS1 (0.52) | TSHRPTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL1069132 | 0.82 | PTGS1 (0.54) | PTGS1PTGS2GSK3AGSK3BMEN1 | |
| Hydrochloric Acid SCHEMBL28991159 | 0.82 | PTGS1 (0.50) | TSHRPTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL4952666 | 0.80 | PTGS1 (0.65) | PTGS1PTGS2GSK3AGSK3BMEN1 | |
| Ethylene Glycol SCHEMBL28669577 | 0.78 | PTGS1 (0.47) | TSHRPTGS1PTGS2GSK3AGSK3B | |
| Succinimide SCHEMBL27157818 | 0.78 | TSHR (0.43) | TSHRPTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL2111664 | 0.77 | PTGS1 (0.76) | PTGS1PTGS2GSK3AGSK3BMEN1 | |
| Alcohol SCHEMBL29133233 | 0.76 | GSK3A (0.55) | TSHRPTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL236431 | 0.75 | TSHR (0.56) | TSHRGSK3AGSK3BMEN1KMT2A | |
| 1,4-Butanediol SCHEMBL5570451 | 0.75 | PTGS1 (0.48) | TSHRPTGS1PTGS2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790171-B | Pyrrolobenzodiazepine dimer precursors and ligand-linker conjugate compounds thereof | 乐高化学生物科学股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112040951-A | Antibody Drug Conjugates (ADC) with NAMPT inhibitors | 拜耳股份公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-111565707-A | Devices and methods for delivering therapeutics | 森玛治疗公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-103130895-A | Specific binding members against synaptophysin | UNIV ABERDEEN | 2013-06-05 | — | — | CN | disclosed |
| EP-1735347-B1 | SPECIFIC BINDING MOLECULES AGAINST SYNAPTOPHYSIN | UNIV ABERDEEN (GB) | 2012-11-07 | — | — | EP | disclosed |
| US-20110165078-A1 | SPECIFIC BINDING MEMBERS AGAINST SYNAPTOPHYSIN | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2011-07-07 | — | — | US | disclosed |
| US-7871782-B2 | Specific binding members against synaptophysin | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2011-01-18 | — | — | US | disclosed |
| US-20080274123-A1 | Specific Binding Members Against Synaptophysin | The University Court of the University of Aberdee n (GB) | 2008-11-06 | — | — | US | disclosed |
| CN-1980958-A | Specific binding members against synaptophysin | UNIV ABERDEEN (GB) | 2007-06-13 | — | — | CN | disclosed |
| EP-1735347-A2 | SPECIFIC BINDING MEMBERS AGAINST SYNAPTOPHYSIN | The University Court of The University of Aberdeen (GB) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005095453-A2 | SPECIFIC BINDING MEMBERS AGAINST SYNAPTOPHYSIN | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165078-A1 | SPECIFIC BINDING MEMBERS AGAINST SYNAPTOPHYSIN | SYPL1, IGSF11, VSIR | TSHR 3312/4885PTGS1 4765/4885PTGS2 4846/4885 |
| US-20080274123-A1 | Specific Binding Members Against Synaptophysin | SYPL1, IGSF11, VSIR | TSHR 3304/4885PTGS1 4756/4885PTGS2 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.