Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52041 | 0.78 | CES2 (0.44) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL3628327 | 0.78 | MAPT (0.52) | CES2ALOX15CA1CA2HSD17B10 | |
| SCHEMBL27750184 | 0.76 | CES2 (0.48) | CES2CES1CA1CA2MAOA | |
| SCHEMBL5379818 | 0.76 | ALDH1A1 (0.48) | CES2CES1GSK3BSRD5A2ATM | |
| SCHEMBL5373801 | 0.76 | TYR (0.48) | MAPK1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL58595 | 0.75 | ALDH1A1 (0.54) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL26095061 | 0.74 | MEN1 (0.32) | HPGDALDH1A1MAPT | |
| SCHEMBL7129303 | 0.74 | POLB (0.53) | ALOX15MAOAMAOBHPGDALDH1A1 | |
| SCHEMBL1673734 | 0.73 | MAPK1 (0.58) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL3622034 | 0.73 | MAPT (0.57) | CES2CES1CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084930-A1 | DIPHENYLPYRIDINE DERIVATIVES, THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2003-10-16 | — | — | WO | disclosed |
| EP-0299362-B1 | PROCESS FOR PREPARING PYRIDINE-2,3- DICARBOXYLIC ACID COMPOUNDS | Daiso Co., Ltd. (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-4948896-A | REACTING AN ENONE AND AN AMINODIESTER | DAISO CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0299362-A1 | Process for preparing pyridine-2,3- dicarboxylic acid compounds | Daiso Co., Ltd. (JP) | 1989-01-18 | — | — | EP | disclosed |