Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7099683 | 0.92 | RECQL (0.39) | RECQLCA2TP53ALDH1A1TDP1 | |
| Monoethanolamine SCHEMBL7958985 | 0.92 | GABRR1 (0.30) | — | |
| Monoethanolamine SCHEMBL7098966 | 0.87 | TP53 (0.40) | RECQLTP53 | |
| Ammonia Solution, Strong SCHEMBL7955239 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL7098132 | 0.80 | RECQL (0.37) | RECQLCA2ALDH1A1TDP1MAPK1 | |
| Monoethanolamine SCHEMBL7099231 | 0.77 | GPR84 (0.36) | RECQLTP53 | |
| Ammonia Solution, Strong SCHEMBL7100038 | 0.77 | TP53 (0.41) | RECQLTP53 | |
| Monoethanolamine SCHEMBL7094954 | 0.77 | CHRM1 (0.36) | TDP1 | |
| SCHEMBL7100584 | 0.76 | CA2 (0.46) | RECQLCA2TP53ALDH1A1TDP1 | |
| Potassium Ion SCHEMBL7098111 | 0.76 | CA2 (0.43) | RECQLCA2TP53ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |