Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162293 | 0.82 | LMNA (0.47) | LMNACYP2C19HIF1A | |
| SCHEMBL1048643 | 0.80 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL7607980 | 0.80 | LMNA (0.47) | LMNACYP2C19HIF1A | |
| SCHEMBL2763433 | 0.80 | LMNA (0.38) | LMNACYP2C19HIF1A | |
| SCHEMBL10318442 | 0.80 | LMNA (0.44) | LMNACYP2C19HIF1A | |
| SCHEMBL15988175 | 0.79 | LMNA (0.47) | LMNACYP2C19HIF1A | |
| SCHEMBL29665118 | 0.79 | CYP2C19 (0.36) | LMNACYP2C19HIF1A | |
| SCHEMBL7056057 | 0.79 | CYP2C19 (0.36) | LMNACYP2C19HIF1A | |
| SCHEMBL8720205 | 0.79 | CYP2C19 (0.36) | LMNACYP2C19HIF1A | |
| SCHEMBL9171058 | 0.78 | LMNA (0.53) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133466-B1 | A PROCESS FOR THE PREPARATION OF N,N'-BIS 2, 3-DIHYDROXYPROPYL] -5-[(HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE | BRACCO INT BV (NL) | 2003-08-20 | — | — | EP | disclosed |