Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038558 | 0.80 | GLA (0.60) | GLAALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL9060376 | 0.78 | GLA (0.59) | GLAALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL5971142 | 0.78 | TSHR (0.52) | GLAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27856601 | 0.76 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4143101 | 0.74 | ALDH1A1 (0.59) | GLAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL9037494 | 0.73 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL11203745 | 0.73 | GLA (0.59) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL25216322 | 0.73 | GLA (0.52) | GLAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3393626 | 0.73 | GLA (0.62) | GLAALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29059492 | 0.73 | GLA (0.55) | GLAALDH1A1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278502-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1278502-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001089451-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |