Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060376 | 0.96 | GLA (0.59) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL9037494 | 0.92 | GLA (0.53) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11063204 | 0.86 | GLA (0.48) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28869016 | 0.82 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL3393626 | 0.82 | GLA (0.62) | GLAALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL2465636 | 0.81 | GLA (0.51) | GLAALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL20224958 | 0.80 | POLB (0.50) | GLAPOLBALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7095053 | 0.80 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL27856601 | 0.80 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL4741712 | 0.80 | ALDH1A1 (0.52) | POLBALDH1A1HTR2CHTR2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |